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November 2015

Volume 1  Issue 2

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Research Article

Trends in the Prevalence of HIV-Seropositivity in Pregnant Women Initiating Antenatal Care in South-South, Nigeria

Hannah E. Omunakwe*, Caroline Iyalla, Dorothy A. Okoh

HIV still remains a pandemic in sub-Saharan Africa, and people of low socio-economic status are more affected by the disease. Nigeria has the largest burden in the West African sub-region with about 2.98 million people living with HIV. Women are most commonly affected by HIV infection and in pregnancy it is associated with complications affecting the mother and the fetus.

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Research Article
Lay Perspectives How HIV/AIDS Prevention Programmes Influenced Selected Urban and Rural South Africans

Hendra van Zyl*, Deborah McGill

South Africa faces a critical public health problem with 6.3 million people living with HIV/AIDS, notwithstanding implementation of the latest biomedical technologies. Worldwide, prevention programmes contributed to reduce HIV incidence. The UNAIDS urged countries to scale-up these programmes. However, South Africa has not experienced predicted reduced HIV incidence.

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Research Article  
Prevalence of Human Leucocyte Antigen HLA-B*5701 among HIV-1 Infected Individuals in South Eastern Nigeria

Nwagu Chinyere, Ureme Samuel, Dick Pere Diweni, Nna Emmanuel, Adegoke Adebayo, Adias Teddy Charles*

Genetic screening, which is also known as DNA-based testing, is a technique employed in testing for hereditary disorders.  It is the analysis of DNA, proteins, and certain metabolites for the purpose of detecting heritable disease-related genotypes, mutations, phenotypes, or karyotypes for clinical reasons. Genetic screening provide vital information on molecular events that underlie a biological pathway, as well as unraveling gene function.

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Research Article

The Burden of Opportunistic-Infections and Associated Exposure Factors among HIV-Patients Admitted at a Botswana Hospital

John Thato Tlhakanelo, Jose Gaby Tshikuka Mulumba*, Mooketsi Molefi, Mgaywa Gilbert Mjungu Damas Magafu, Reginald Blessing Matchaba-Hove and Tiny Masupe

Botswana is among countries most affected by the human immunodeficiency virus (HIV) pandemic. Since 2001, aggressive interventions have been launched by the government including free access to combination antiretroviral treatment (cART). cART is known to reduce HIV transmission, related morbidities and hospital admissions among people living with HIV (PLWH). However, hospital admissions among PLWH in Botswana still remain high. Factors associated with such admissions have not yet been highlighted. Even though opportunistic infections (OIs) have been incriminated as the major cause of admissions among PLWH, the OIs have not yet been meticulously studied in Botswana.

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Research Article

Correlates of Hospital Admissions due to Non-Opportunistic Infections Including Attempted Suicide among HIV Patients at a Botswana Referral Hospital

Jose Gaby Tshikuka Mulumba*, Ph.D., John Thato Tlhakanelo, Bsc, MBChB., Mooketsi Molefi, MBChBSc., Mgaywa Gilbert Mjungu Damas Magafu, MD, MPHM, MPH, MSc, Ph.D., Reginald Blessing Matchaba-Hove, MBChB, MSc., Tiny Masupe, MBChB, MPH., MSc. Naoko Shimizu Magafu, BSc, MNS

Hospital admissions among people living with HIV (PLWH) are generally attributed to opportunistic infections (OIs), yet conditions other than OIs also account for a number of admissions among PLWH. Correlates of such admissions among PLWH have not been sufficiently investigated so the need for such an investigation is critical to inform health policies and priorities. This work highlights non-OIs conditions responsible for admission of PLWH at Princess Marina Hospital (PMH), one of the two main referral hospitals for HIV patients in Botswana, and identifies correlates of the admissions to inform
health policies and priorities.

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